Abisil®

Plant-based drug

• Areas of use

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    Treatment of symptoms and prevention of acute respiratory infections and influenza
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    Treatment of wounds and trophic ulcers
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    Treatment of inflammatory diseases of the nasopharynx and ear
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    Treatment of adenoiditis
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    Treatment of periodontal disease and complications after dental prosthetics
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    Treatment of pyoderma and acne
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    Treatment of burns, fistulas, purulent-inflammatory diseases of the skin and soft tissues

• Description

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  The drug Abisil (Abisilum – 20% solutio oleose) is a multicomponent mixture of biologically active substances derived from Siberian Fir (Abies sibirica Led.) and dissolved in sunflower oil. The drug contains a natural set of terpenoids synthesized by the epithelial cells of this coniferous tree.

  The study of the chemical composition of this drug, including the use of gas-liquid chromatography, has shown that it contains mainly monocyclic and bicyclic monoterpenoids, sesquiterpenoids, diterpene and triterpene acids.

  The study of the harmlessness of Abisil carried out in laboratory animals (Guinea pigs, rats and white mice) has revealed that it does not cause any toxic or allergic reactions, does not have any mutagenic or embryotoxic effects.

  These studies have determined a wide spectrum of pharmacological activity of Abisil: anti-inflammatory, immunomodulating, antimicrobial, wound healing, analgesic, and antitumor.

• Instruction

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  INSTRUCTIONS
  FOR MEDICAL USE OF
  A MEDICINAL PRODUCT Abisil®

   

  Registration number: ЛП-№ (007393)- (РГ-RU) of 25.10.2024

  Trade name – Abisil ®

  Dosage form: Oil solution for local and external use

  Composition: 100 g contains:
  Active substance: Abisil (Siberian fir terpenes) with a bornyl acetate content of at least 10% – 20 g.
  Excipients: sunflower oil – up to 100 g.

  Description:

  A thick, oily liquid ranging from yellow to milky-white in color with a characteristic odor.
  Separation may occur during storage, but it disappears upon shaking.

   

  PHARMACOTHERAPEUTIC GROUP

  Other therapeutic agents.

   

  ATC-CODE: V03AX

  Pharmacological properties 

  Pharmacodynamics

  The product has pronounced anti-inflammatory, wound-healing, antibacterial, analgesic, and anti-exudative effects due to the properties of the natural terpenoids in its composition.

  It has abroad spectrum of antimicrobial activity against gram-positive and gram-negative bacteria, including antibiotic-resistant strains.

  It develops optimal conditions for wound healing in soft tissues, accelerates epithelialization, and improves microcirculation.
  The product is non-toxic, and no teratogenic, mutagenic, or carcinogenic effects have been identified, which allows for its use in all age groups.

  Pharmacokinetics

  When applied locally and externally, the drug is not absorbed, therefore, pharmacokinetic studies are not possible.

  INDICATIONS FOR USE

  The drug is indicated for use in the following conditions:
  In otolaryngology: otitis, eustachitis, sinusitis, rhinitis, nasopharyngitis, pharyngitis, tonsillitis, conditions after tonsillectomy, laryngitis.
  In dentistry: periodontosis, stomatitis, gingivitis, alveolitis, complications with dental prosthetics.
  In dermatology: erysipelas, pyoderma (superficial staphylo- and streptoderma).
  In general surgical practice: purulent-inflammatory diseases of the skin and soft tissues (trophiculcers and long-term non healing purulent postoperative and post-traumatic wounds, fistulas, bedsores, burns and frostbite, abscesses and phlegmons, including those of the maxillofacial region).

  CONTRAINDICATIONS

  Hypersensitivity to the components of the drug.

  Posology and method of administration:
  Locally, externally.
  For otitis: insert a swab soaked in the drug into the external auditory canal.
  For the treatment of rhinitis, sinusitis: instill 1-2 drops into each nasal passage 3-4 times a day.
  For maxillary sinusitis: introduce the drug into the maxillary sinus after its preliminary sanitation.
  For the treatment of tonsillitis and other inflammatory diseases of the throat: treat mucous membranes with the drug 2-3 times a day.

  For inflammatory processes in the maxillofacial region: after incision and surgical treatment of abscesses and phlegmons, insert swabs soaked in the drug into the pockets and postoperative wounds. Repeat the procedure daily for 5-7 days.
  For diseases of the oral cavity: treat the affected surface of the mucous membrane 2-3 times a day or use swabs soaked in the drug.
  For skin diseases (erysipelas, pyoderma): apply the drug in a thin layer to the affected areas 1-3 times daily. The duration of treatment is individual and depends on the severity of the disease.
  For purulent-inflammatory diseases of the skin and soft tissues: after surgical treatment, apply the drug 1-2 times daily in a thin, even layer. The duration of treatment depends on the type and severity of the disease (usually 5-10 days) and ends when fresh granulation, epithelial islands, or complete epithelialization appears.
  If there is no improvement during treatment, or symptoms worsen, or new symptoms appear, consult a doctor.
  Use the drug only as directed by the instructions in terms of indications, method of administration, and doses.

  Side effect:
  Allergic reactions are possible, including ones in patients with hypersensitivity to essential oils, as well as a short-term burning sensation at the application site.
  If you experience any of the side effects listed in the instructions, or if they worsen, or if you notice any other side effects not listed in the instructions, please notify your doctor.

  Overdose:
  To date, no information on drug overdose has been recorded.

  Drug-drug interaction:
  Do not combine with other external agents.

  Special instructions:
  Shake the bottle before use.
  Avoid contact with the conjunctiva of the eye. If contact occurs, rinse with water.
  Do not apply to wet skin.

  Effect on the ability to drive vehicles and operate machinery:
  The use of the drug does not affect the ability to perform potentially hazardous activities that require increased concentration and speed of psychomotor reactions (driving vehicles, operating moving mechanisms, working as a dispatcher, operator).

  Presentation:
  20% oil solution for topical and external use.

  5, 10, 15, 20, 30, and 50 ml, or 100 ml each in amber glass vials, sealed with polyethylene stoppers and plastic screw caps.

  5, 10, 15, 20, 30, and 50 ml, or 100 ml each in cinnamon glass dropper bottles, sealed with tamper-evident screw caps and a dropper.

  10, 15, 20, 30, and 50 ml each in cinnamon glass vials, sealed with screw caps and a pipette.

  15, 20, and 25 ml each in amber glass dropper bottles, sealed with a dropper stopper and caps.

  Each bottle or dropper bottle, along with instructions for use, is in a cardboard box.

  Storage conditions:
  Store in a dry, dark place at a temperature not exceeding 25°C.
  Keep out of reach of children.

  Shelf life:
  5 years.
  Do not use after expiry date.

  Dispensing rules:
  OTC drug.

  Marketing authorization holder:
  Initium-Pharm LTD, Russia
  7, Kashirskoye sh., office 509 B, Domodedovo, Moscow region, 142001
  tel.: +8 800 234-83-04
  www.initium-pharm.com

  Manufacturer/organization accepting claims:
  Tatchempharmpreparaty JSC, Russia
  260, Belomorskaya ul., Kazan, 420091
  tel.: (843) 571-85-58;
  fax: (843) 571-85-38
  e-mail: marketing@tatpharm.ru

• Advantage

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  • 
    Activates the internal protection of a human
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    You can use this product for children
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    Completely natural
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    Contains more than 300 species of terpenes
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    In therapeutic doses does not cause side effects
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    Not addictive