The drug Abisil (Abisilum – 20% solutio oleose) is a multicomponent mixture of biologically active substances derived from Siberian Fir (Abies sibirica Led.) and dissolved in sunflower oil. The drug contains a natural set of terpenoids synthesized by the epithelial cells of this coniferous tree.
The study of the chemical composition of this drug, including the use of gas-liquid chromatography, has shown that it contains mainly monocyclic and bicyclic monoterpenoids, sesquiterpenoids, diterpene and triterpene acids.
The study of the harmlessness of Abisil carried out in laboratory animals (Guinea pigs, rats and white mice) has revealed that it does not cause any toxic or allergic reactions, does not have any mutagenic or embryotoxic effects.
These studies have determined a wide spectrum of pharmacological activity of Abisil: anti-inflammatory, immunomodulating, antimicrobial, wound healing, analgesic, and antitumor.
INSTRUCTION FOR MEDICAL USE ABISIL (Brief information)
Registration number: Р No. 003339/02
Commercial name – ABISIL INN (international nonproprietary name): Abies sibirica terpens
Dosage form: solution for local and external application (oil-based)
INDICATIONS FOR USE
In Dental Surgery: stomatitis, parodontosis, gingivitis, denture treatment complications.
In Dermatology: erysipelatous inflammation, pyoderma.
DOSAGE AND ADMINISTRATION: local and external application.
In case of pyo-inflammatory diseases of the skin and soft tissues, it is required to carry out the preliminary surgical treatment of the wound surface. After that, a uniform thin layer of the drug is applied 1-2 times a day. The duration of treatment depends on the form and severity of the disease (generally, from 5 to 10 days). The treatment should be terminated after the appearance of fresh granulations, epithelial islets or complete epithelialization.
In case of stomatopathy, it is required to treat the affected surface of the mucous membrane 2-3 times a day or apply cotton swabs moistened with the drug.
In case of otitis, it is required to enter a tampon moistened with the medicine into the external ear canal.
When treating tonsillitis and other inflammatory diseases of the throat, it is required to treat the mucous membranes with the drug 2-3 times a day.
INTERACTIONS WITH OTHER MEDICINAL PRODUCTS
PHARMACEUTICAL FORM AND PRESENTATION
(843) tel.571-85-58; fax 571-85-38 (KZ)
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