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Medicinal product based on terpenes

Abisil®

Plant-based drug

  • Areas of use

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    • Abisil®
      Treatment of symptoms and prevention of acute respiratory infections and influenza

  • Description

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    The drug Abisil (Abisilum – 20% solutio oleose) is a multicomponent mixture of biologically active substances derived from Siberian Fir (Abies sibirica Led.) and dissolved in sunflower oil. The drug contains a natural set of terpenoids synthesized by the epithelial cells of this coniferous tree.

    The study of the chemical composition of this drug, including the use of gas-liquid chromatography, has shown that it contains mainly monocyclic and bicyclic monoterpenoids, sesquiterpenoids, diterpene and triterpene acids.

    The study of the harmlessness of Abisil carried out in laboratory animals (Guinea pigs, rats and white mice) has revealed that it does not cause any toxic or allergic reactions, does not have any mutagenic or embryotoxic effects.

    These studies have determined a wide spectrum of pharmacological activity of Abisil: anti-inflammatory, immunomodulating, antimicrobial, wound healing, analgesic, and antitumor.

  • Instruction

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    INSTRUCTION FOR MEDICAL USE ABISIL (Brief information)

     

    Registration number: Р No. 003339/02

    Commercial name – ABISIL INN (international nonproprietary name): Abies sibirica terpens

    Dosage form: solution for local and external application (oil-based)

     

    FORMULA:

    Active agent: Abisil (Abies sibirica terpens) with Bornyl acetate content of 10.0% – 20.0 g
    Additive agent: Sunflower oil – up to 100 g

     

    PHARMACOTHERAPEUTIC GROUP

    PLANT-BASED ANTI-INFLAMMATORY MEDICINE

     

    ATC-CODE: [D06BX]

    PHARMACOLOGY

    The drug has a pronounced anti-inflammatory, wound-healing, antibacterial, analgesic, and anti-exudative effect due to the properties of natural terpenoids included in its formula. It has a wide spectrum of antimicrobial activity against Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains. It creates optimal conditions for healing the wound surface of soft tissues, accelerates the epithelialization process, and improves microcirculation. In case of local application, it is not absorbed and does not have a local irritative effect. The drug has no toxic properties. No teratogenic, mutagenic or carcinogenic effects have been found, which makes it possible to use it in all the age groups.

     

    INDICATIONS FOR USE

    In General Surgery practice: pyo-inflammatory diseases of the skin and soft tissues (trophic ulcers and long-term non-healing septic surgical and post-traumatic wounds, fistulas, pressure injuries, burns and freeze burns, abscesses and cellulitis, including maxillofacial area).

    In Dental Surgery: stomatitis, parodontosis, gingivitis, denture treatment complications.

    In Otorhinolaryngology: otitis, eustachitis, sinusitis, rhinitis, rhinopharyngitis, pharyngitis, tonsillitis, status post tonsillectomy, laryngitis, etc.

    In Dermatology: erysipelatous inflammation, pyoderma.

     

    CONTRAINDICATIONS

    Individual intolerance to components

    DOSAGE AND ADMINISTRATION: local and external application.

    In case of pyo-inflammatory diseases of the skin and soft tissues, it is required to carry out the preliminary surgical treatment of the wound surface. After that, a uniform thin layer of the drug is applied 1-2 times a day. The duration of treatment depends on the form and severity of the disease (generally, from 5 to 10 days). The treatment should be terminated after the appearance of fresh granulations, epithelial islets or complete epithelialization.

    In case of inflammatory processes in the maxillofacial area, after opening and surgical treatment of abscesses and cellulitis, it is required to enter the tampons impregnated with Abisil solution into the pockets and surgical wounds. The procedure is repeated daily from 5 to 7 days.

    In case of stomatopathy, it is required to treat the affected surface of the mucous membrane 2-3 times a day or apply cotton swabs moistened with the drug.

    In case of otitis, it is required to enter a tampon moistened with the medicine into the external ear canal.

    When treating rhinitis or sinusitis, it is required to inject 1-2 drops in each nasal passage. The procedure should be repeated 3-4 times a day. In case of sinus infection, the medicine is injected into the maxillary sinus after its preliminary sanitation.

    When treating tonsillitis and other inflammatory diseases of the throat, it is required to treat the mucous membranes with the drug 2-3 times a day.

    In case of skin diseases, a thin layer of the drug is applied 1 to 3 times a day on the affected areas. The duration of the course is individual and depends on the severity of the disease.

     

    ADVERSE EFFECTS

    Impermanent burning in the place of application of the drug. People with hypersensitivity to essential oils may have allergic reactions.

     

    INTERACTIONS WITH OTHER MEDICINAL PRODUCTS

    Do not combine it with other external remedies.

     

    PRECAUTIONS

    Shake the drug bottle before application. Keep the medicine away from the eye conjunctiva, if it gets there, rinse the eyes with water. Do not apply on the wet skin.

     

    PHARMACEUTICAL FORM AND PRESENTATION

    20% solution for local and external application (oil-based).

     

    STORAGE CONDITIONS

    In a dry dark place at the temperature not exceeding 25 °C. Keep away from children.

     

    SHELF-LIFE

    4 years. Do not use after the date specified on the package.

     

    PRESCRIPTION STATUS

    No prescription.
    Please read the detailed instructions before using the drug.
    The information is intended only for health professionals. It can be distributed only in the framework of activities related to professional development of medical and pharmaceutical workers, including specialized exhibitions, conferences, etc.

    (843) tel.571-85-58; fax 571-85-38 (KZ)

    E-mail: marketing@tatpharm.ru

  • Advantage

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    • Abisil®
      Activates the internal protection of a human